MSM For Horses
One of the most commonly fed horse supplement ingredients, MSM is well-known for its antioxidant and other properties which support healthy joints, skin and coat, hooves, the respiratory tract, and other tissues in horses. It provides a highly usable form of sulfur which plays a critical role the formation of proteins such as enzymes, hormones, and immune cells, as well as connective tissue such as bones, tendons, and ligaments.
Sources and Bioavailability of MSM for Horses
According to a study*, MSM has the highest absorption rate (55%) of all the key equine joint ingredients, making it available for use in tissues throughout the horse's body. Although naturally-occurring in foods such as alfalfa and whole grains, the amount of MSM from the horse's diet is unlikely to be a significant contributor compared to supplementing with the pure ingredient.
Serving size: A group of European researchers studied the effects of MSM on biomarkers of oxidative stress in horses following jumping exercise by giving 4,000 mg to an 1100 lb horse. While protective benefits were seen from this amount, typical serving sizes range from 5,000-10,000 mg/day, with some equine veterinary dermatologists recommending as much as 10,000-12,000 mg twice a day as a loading dose.
Complementary ingredients: A randomized, double-blind, placebo-controlled study showed that the combination of MSM and glucosamine worked better to maintain equine joint health than either ingredient alone.
Toxicity/Side Effects: MSM is one of the least toxic substances in biology, with no known side effects documented in any species to date. It has an excellent track record of safety in the horse.
Not sure which supplement is right for your horse? We have compiled comparison charts so that you can compare active ingredient amounts in the following categories of Joint Supplements and Comfort Supplements.
*Source: Proc 17th Equine Nutr Physiol Soc:141-2. A study of the absorption of methylsulfonylmethane in horses. Pratt SE, Clarke AF, Riddolls L, McKee S
MSM for horses is now available in tasty pellets! MSM is a naturally occurring sulfur compound known for its ability to help horses with stiffness and discomfort associated with exercise and normal daily activity. In addition, this economical supplement may help with itchy skin due to environmental or seasonal conditions, and may also help maintain normal respiratory function. Research has shown that MSM protects tissues against the damaging effects of exercise and stress. Smart & Simple MSM Pellets for Horses provides 10,000 mg of 99% pure MSM (Methylsulfonylmethane) in a tasty pellet that horses love!
MSM is a naturally occurring sulfur compound known for its ability to help horses with stiffness and discomfort associated with exercise and normal daily activity. In addition, this economical supplement may help with itchy skin due to environmental or seasonal conditions, and may also help maintain normal respiratory function. Research has shown that MSM protects tissues against the damaging effects of exercise and stress. Smart & Simple MSM provides 10,000 mg of 99% pure MSM (Methylsulfonylmethane) in a sugar-free berry-flavored powder that horses love!
Select the Best's MSM is an ultra-pure 99.9% source of bio-available sulfur. MSM, or methylsulfonylmethane, is thought to support a healthy inflammatory response. No fillers, artificial colors, or flavors.
Cosequin® is the #1 veterinarian recommended joint health supplement brand*. Cosequin Optimized with MSM is a tasty powder containing higher levels of active ingredients compared to the original researched formula, with the addition of high-quality MSM (methylsulfonylmethane). This supplement is a convenient way to provide MSM along with the scientifically researched ingredients in original Cosequin. When performance matters, choose Cosequin.
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
- Joint Health Support for Horses: This supplement is formulated with glucosamine, chondroitin sulfate, and methylsulfonylmethane (MSM) to support joint health.
- Optimized Formula with MSM: This supplement is a convenient way to provide MSM along with the proven ingredients in the original Cosequin formula.
- Easy to Serve: Cosequin Optimized Equine Joint Health Supplements come in an easy to administer tasty powder.
- Formulated for Your Horse: The researched ingredients in Cosequin work together to help protect the cartilage in your horse’s joints by supporting healthy cartilage matrix as well as inhibiting certain enzymes that break down cartilage.
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to support your horse’s joint health, no matter their discipline or performance level.
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
Arthroxigen Pellets™ provide building blocks for healthy joints and soft tissues. This pelleted formula promotes joint mobility, structural integrity, and function with key ingredients such as glucosamine, chondroitin sulfate, MSM, and hyaluronic acid. Enhanced by substantial levels of hydrolyzed collagen and the inclusion of eggshell membrane, this supplement goes above normal joint care with support for bone, cartilage, and connective tissues. Arthroxigen additionally supports overall health and a normal response to inflammation with devil’s claw, resveratrol, vitamin C, boswellia, goldenrod, and yucca. Arthroxigen is an ideal high-powered support option for horses needing support for activity, training, or everyday wear and tear.
Note: Do not feed to pregnant mares. Contains a prohibited substance.
Also available as Arthroxigen™ Powder.
- Full-range support for joint, connective tissue, bone, cartilage, and overall body health
- Promotes a normal response to inflammation
- Formulated for horses needing added support for activity, training, or everyday wear and tear.
Note: Do not feed to pregnant mares. Contains a prohibited substance.
Also available as Arthroxigen™ Powder.
Your horse’s body has the ability to repair and rebuild after normal “wear and tear” from light activity, but the increasing demands of riding and training could cause more damage than it can keep up with. Joint supplements in this category are designed for horses in heavy work to help support your horse by providing a steady supply of the ingredients he needs to cope with the demands of his workload. This level of support is also worth considering for horses in lighter workloads that may benefit from additional support due to factors like age or previous joint issues.
Even light work can lead to wear and tear on your horse's joints; after all, researchers have found that even wild mustangs can develop joint issues. That's why providing your young horse, or horse in light work with basic joint support is a sound investment in your future together.
Even light work can lead to wear and tear on your horse's joints; after all, researchers have found that even wild mustangs can develop joint issues. That's why providing your young horse, or horse in light to moderate work with the fundamentals of joint health is a sound investment in your future together.
Cosequin® is the #1 veterinarian recommended joint health supplement brand*. Cosequin Optimized with MSM is available in a tasty pellet containing higher levels of active ingredients compared to the original researched Equine formula, with the addition of high-quality MSM (methylsulfonylmethane). This supplement is a convenient way to provide MSM along with the scientifically researched ingredients in original Cosequin.? When performance matters, choose Cosequin.
Also available as a powder! Cosequin® Optimized with MSM
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
- Pelleted Joint Health Support for Horses: This supplement is formulated with glucosamine, chondroitin sulfate, and methylsulfonylmethane (MSM) to support joint health.
- Easy to Feed: Cosequin Optimized Equine Joint Health Pellets Supplements come in an easy to administer tasty pellet.
- Optimized Formula with MSM: a convenient way to provide MSM along with the proven ingredients in the original Cosequin Equine formula.
- Formulated for Your Horse: The researched ingredients in Cosequin work together to help protect the cartilage in your horse’s joints by supporting healthy cartilage matrix as well as inhibiting certain enzymes that break down cartilage.
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to support your horse’s joint health, no matter their discipline or performance level.
Also available as a powder! Cosequin® Optimized with MSM
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
Glucosamine XL Plus with MSM supports healthy joint function with 8,000 mg of glucosamine, 10,500 mg of MSM, 1,000 mg of Ester-C, 100 IUs of vitamin E and 125 mg of yucca. Horses love these tasty pellets!
Dealing with respiratory problems can be stressful, especially since they can impact overall health and performance. In addition to veterinary care and a management plan, the right combination of ingredients can also help support healthy lung function in horses with respiratory issues, so you and your horse can enjoy your rides!
Leg Up® Joint Senior Pellets provide joint support designed specifically for older horses in convenient pellets. This formula provides glucosamine and chondroitin sulfate to support cartilage health. It also includes MSM, which is known for its ability to help horses with stiffness and discomfort associated with normal exercise and aging. A healthy response to inflammation is addressed with yucca and boswellia, while MSM and 2,000 mg of turmeric serve double duty as both antioxidants and normal inflammatory response support. Finally, because senior horses may benefit from additional vitamin C, this important antioxidant is included to help support joints and connective tissue as well as overall health and well being. This is an excellent choice if you’re looking for senior joint support at an outstanding value, all in a tasty pellet that your horse will love.
Cosequin® is the #1 veterinarian recommended joint health supplement brand*. Cosequin ASU is veterinarian formulated with avocado/soybean unsaponifiables (ASU), glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), and boswellia serrata extract to provide joint health support for equine athletes regardless of discipline or performance level. When performance matters, choose Cosequin.
- Joint Health Support for Horses: This supplement is formulated with glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), and avocado/soybean unsaponifiables (ASU) to support joint health.
- Powered by ASU: The combination of ASU, glucosamine, and chondroitin found in Cosequin ASU have been shown to be more effective supporting joint health than either glucosamine or chondroitin sulfate alone in cell culture studies.
- Easy to Serve: Cosequin?ASU Pellets combine our scientifically researched, proprietary ingredients into a tasty, tiny pellet preferred by horses and horse owners.
- Formulated for Your Horse: ASU complements the positive effects of the glucosamine and chondroitin sulfate in Cosequin ASU, providing broad spectrum joint support for the equine athlete.
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to support your horse’s joint health, no matter their discipline or performance level.
Cosequin® is the #1 veterinarian recommended joint health supplement brand*. Cosequin ASU Plus is veterinarian formulated with avocado/soybean unsaponifiables (ASU), glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), boswellia serrata extract, green tea extract and HA to provide joint health support for equine athletes regardless of discipline or performance level. When performance matters, choose Cosequin.
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
- Joint Health Support for Horses: This supplement is formulated with glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), avocado/soybean unsaponifiables (ASU), green tea extract and hyaluronic acid to support joint health.
- Powered by ASU: The combination of ASU, glucosamine, and chondroitin found in Cosequin ASU have been shown to be more effective supporting joint health than either glucosamine or chondroitin sulfate alone in cell culture studies.
- High Quality Ingredients: Avocado/soybean unsaponifiables, or ASU, is derived from avocados and soybeans. Studies using cartilage cells have shown that ASU inhibits the expression of several components involved in the process of cartilage breakdown in joints.
- Formulated for Your Horse: The combination of ASU, glucosamine, chondroitin sulfate, with HA was shown to be more effective in reducing the expression of several factors involved in the breakdown of cartilage than ASU, glucosamine, chondroitin sulfate or HA alone in cell culture studies.
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to support your horse’s joint health, no matter their discipline or performance level.
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
Cosequin® is the #1 veterinarian recommended joint health supplement brand*. Cosequin ASU is veterinarian formulated with avocado/soybean unsaponifiables (ASU), glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), and boswellia serrata extract to provide joint health support for equine athletes regardless of discipline or performance level. When performance matters, choose Cosequin.
For the next level in joint support, consider Cosequin ASU® Plus!
- Joint Health Support for Horses: This supplement is formulated with glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), and avocado/soybean unsaponifiables (ASU) to support joint health.
- Powered by ASU: The combination of ASU, glucosamine, and chondroitin found in Cosequin ASU have been shown to be more effective supporting joint health than either glucosamine or chondroitin sulfate alone in cell culture studies.
- High Quality Ingredients: Avocado/soybean unsaponifiables, or ASU, is derived from avocados and soybeans. Studies using cartilage cells have shown that ASU inhibits the expression of several components involved in the process of cartilage breakdown in joints.
- Formulated for Your Horse: ASU complements the positive effects of the glucosamine and chondroitin sulfate in Cosequin ASU, providing broad spectrum joint support for the equine athlete.
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to support your horse’s joint health, no matter their discipline or performance level.
For the next level in joint support, consider Cosequin ASU® Plus!
Lubrigen Pellets™ provide proactive joint support for young or heavily worked horses. Formulated to help maintain strong bones, joint mobility, synovial fluid, structural integrity, and function with high quantities of top ingredients. Lubrigen contains glucosamine, chondroitin, and MSM, plus 13 additional ingredients to give your horse well rounded joint and connective tissue support. Provided in high amounts, glucosamine, chondroitin, and hyaluronic acid support joint mobility. MSM and collagen provide support for connective tissues, and MSM additionally helps to maintain a normal inflammatory response. To support strong structural integrity, Lubrigen includes silica, calcium ascorbate, pantothenate, and fatty acids. Lastly, to optimize protection from damaging free radicals, there is lysine, methionine, and grape seed extract.
Every horse is unique and so are his needs, however many horses can benefit from support in several key areas, no matter their workload or discipline. Multi-purpose formulas target specific areas to give your horse a solid foundation for success all in one formula. From the elite equine athlete to the retired senior, there is a perfect combo for your best friend.
Cosequin® is the #1 veterinarian recommended joint health supplement brand*. Cosequin ASU Joint & Hoof Pellets are veterinarian formulated with avocado/soybean unsaponifiables (ASU), glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), and boswellia serrata extract to provide joint health support for equine athletes regardless of discipline or performance level. The addition of biotin, copper, zinc and essential amino acids methionine and lysine provides comprehensive hoof support to promote hoof durability, strength, and growth. When performance matters, choose Cosequin.
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
- Joint Health Support for Horses: This supplement is formulated with glucosamine, chondroitin sulfate, methylsulfonylmethane (MSM), and avocado/soybean unsaponifiables (ASU) to support joint health.
- Powered by ASU: The combination of ASU, glucosamine, and chondroitin found in Cosequin ASU have been shown to be more effective supporting joint health than either glucosamine or chondroitin sulfate alone in cell culture studies.
- Easy to Serve: Cosequin?ASU Joint & Hoof Pellets combine our scientifically researched, proprietary ingredients into a tasty, tiny pellet preferred by horses and horse owners.
- Formulated for Your Horse: The addition of biotin, copper, zinc and essential amino acids methionine and lysine provides comprehensive hoof support to promote hoof durability, strength and growth.
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to support your horse’s joint health, no matter their discipline or performance level.
*Survey conducted among equine veterinarians who recommended oral joint health supplements.
All-inclusive horse joint supplement. Flex+Max® offers comprehensive joint care featuring enhanced ingredient levels for guaranteed results—all in a horse joint supplement offering a highly palatable formula with no fillers. Flex+Max also offers “guaranteed levels of glucosamine and chondroitin,” which is important when you consider that levels of active ingredients in supplements can vary widely, impacting the results they’re able to deliver. Formulated with 10,000 mg of glucosamine, 1,200 mg of chondroitin sulfate, 5,000 mg of MSM & 150 mg of HA.
Made in the USA
Made in the USA
SmartFlex Senior Herb-Free Pellets are designed to provide well-rounded joint support for older horses. This herb-free version of SmartFlex Senior is ideal for older horses that compete.
For joint support, SmartFlex Senior Herb-Free Pellets provide 8,000 mg of glucosamine, 700 mg of chondroitin sulfate, 75 mg hyaluronic acid, and 12,000 mg of MSM. This formula also contains 500 mg of the amino acid phenylalanine to help address stiffness and discomfort associated with aging. And because senior horses benefit from extra antioxidants, this supplement also contains vitamin C and super oxide dismutase. Your horse will love these tasty pellets! For even more comprehensive senior support, consider our multi-purpose formula SmartCombo Senior Ultra Pellets.
For joint support, SmartFlex Senior Herb-Free Pellets provide 8,000 mg of glucosamine, 700 mg of chondroitin sulfate, 75 mg hyaluronic acid, and 12,000 mg of MSM. This formula also contains 500 mg of the amino acid phenylalanine to help address stiffness and discomfort associated with aging. And because senior horses benefit from extra antioxidants, this supplement also contains vitamin C and super oxide dismutase. Your horse will love these tasty pellets! For even more comprehensive senior support, consider our multi-purpose formula SmartCombo Senior Ultra Pellets.
Every horse is unique and so are his needs, however many horses can benefit from support in several key areas, no matter their workload or discipline. Multi-purpose formulas target specific areas to give your horse a solid foundation for success all in one formula. From the elite equine athlete to the retired senior, there is a perfect combo for your best friend.
Supplements in this category are highly targeted to support normal recovery in horses. They provide active ingredient profiles to help give the body what it needs to support a healthy inflammatory response and encourage normal healing.
Equithrive® Complete Joint Pellets combine Equithrive® Original Joint with the added benefits of Equithrive® Essential Joint to create a comprehensive joint supplement perfect for horses dealing with aging, training, or competition. This formula contains a proprietary microencapsulated resveratrol product, Resverasyn®. This bioavailable form of resveratrol produces high circulating levels of resveratrol after oral administration for maximum effect in protecting against free radical damage. Equithrive® Complete has undergone extensive scientific testing at leading equine research institutions to study the effects of resveratrol and its relationship with healthy joint support.
Equithrive® Complete Joint Pellets also include high levels of ingredients that are key to connective tissue support, including glucosamine, chondroitin sulfate, and hyaluronic acid (HA). These ingredients support the normal formation and maintenance of cartilage and synovial fluid. This product also contains methylsulfonylmethane (MSM), which aids Resveraysn in promoting a healthy inflammatory response in horses.
Equithrive® Complete Joint Pellets also include high levels of ingredients that are key to connective tissue support, including glucosamine, chondroitin sulfate, and hyaluronic acid (HA). These ingredients support the normal formation and maintenance of cartilage and synovial fluid. This product also contains methylsulfonylmethane (MSM), which aids Resveraysn in promoting a healthy inflammatory response in horses.
Normal aging and years of work can really take a toll on joints, causing stiffness and discomfort that can make a senior horse’s life more difficult. By providing your old friend with joint support designed to help keep him comfortable, you’re showing him how much you love him and appreciate the years you’ve shared.
Your horse’s body has the ability to repair and rebuild after normal “wear and tear” from light activity, but the increasing demands of riding could cause more damage than it can keep up with. Joint supplements in this category are designed for horses in intense work and provide the ingredients needed to help maintain joints and connective tissue health. Tendon and ligament ingredients as well as a comprehensive selection of antioxidants are included to help equine athletes continue to thrive. This level of support is also worth considering for horses that may need additional support due to age or joint issues.
Senior Flex H/A is a unique combination of joint, digestive and antioxidant support for the senior horse. Provides 50 mg of hyaluronic acid, 5,000 mg of glucosamine, 500 mg of chondroitin sulfate, 5,000 mg of MSM, 5,500 mg of yucca, 1,200 mg of calcium ascorbate, 15,000 IUs of vitamin A, 1,000 IUs of vitamin E, and probiotics to aid in maintaining body condition and digestive function. Your senior horse will love these tasty pellets!
Your horse’s joint health is key to his longevity and comfort, but even light work can lead to wear and tear on your horse’s joints. After all, researchers have found that even wild mustangs can develop joint issues. That’s why providing your horse with ingredients to support healthy joints, cartilage, and soft tissue is a sound investment in your future together.
SmartTendon Pellets provide targeted support for tendons and ligaments to help keep your horse going strong for years to come! This cutting-edge formula contains carefully selected key ingredients, including 4,000 mg of hydrolyzed collagen, to help provide your horse’s body with what it needs for resilient tendons and ligaments. It also contains 300 mg of silica, a trace mineral that’s vital for connective tissue health, but may not be found in adequate levels in many horses’ diets. Additionally, it includes 2,500 mg of MSM, which has been shown to protect tissues against the damaging effects of exercise and stress. Lastly, SmartTendon Pellets provide the antioxidant vitamin C, which is also important in the production of connective tissue. This unique formula can be given alone or combined with your favorite joint supplement. SmartTendon Pellets are the ideal way to help maintain your performance horse’s soft tissue health or to support your horse in recovery.
Grand Complete is a broad-based supplement that supports joints, hooves, and coat. Grand Complete provides 2,500 mg of glucosamine, 2,500 mg of MSM, 2,500 mg of vitamin C, 10 mg of biotin, and 3,000 mg of methionine, along with antioxidants, yeast, and minerals. Grand Complete also provides omega 3 and 6 fatty acids from soy and flaxseed, to help promote a shiny coat!
Learn more about Grand Complete
Learn more about Grand Complete
Airway EQ Pellets are a daily respiratory supplement with comprehensive support for healthy lungs and soft tissue throughout the respiratory tract that also helps maintain a normal immune response to seasonal allergies. It contains 3,000 mg of spirulina, a powerful antioxidant that helps support the immune system and plays a significant role in supporting a normal inflammatory response. It's also been shown to help support symptoms associated with inflammation of the nasal passage triggered by allergens. N-Acetyl L-Cysteine is associated with supporting normal inflammatory responses in the lung and bronchial tissues while a hearty dose of MSM provides additional inflammatory response throughout the body. A healthy immune system is addressed with a variety of key ingredients, including grape seed extract, while citrus bioflavonoids, hawthorn, probiotics, and vitamin K are included for their role in immune health. Finally, a hefty 5,000 IUs of vitamin A aim to support soft tissue repair and a healthy immune system.
SmartComfort™ Pellets provide a potent combination of ingredients to help your horse’s body address the stiffness and discomfort associated with exercise and aging. This comprehensive formula provides carefully selected herbs and other ingredients such as devil's claw, yucca, MSM and cetylated fatty acids to help support your horse's comfort. It also provides potent antioxidants such as vitamin C and turmeric root to fight oxidative stress and support a normal response to inflammation. SmartComfort™ Pellets are perfect for adult and senior horses that need added support for day-to-day stiffness and aches.
Dealing with respiratory problems can be stressful, especially since they can impact your horse’s overall health and performance. In addition to veterinary care and a management plan, the right combination of ingredients can also help support healthy lung function in horses with respiratory issues, so you and your horse can enjoy your rides!
This innovative hoof health formula includes hops and omega 3 fatty acids, two ingredients demonstrated by research to support healthy laminae. SmartLamina Pellets also include the super-potent antioxidant Auradagex™ to combat oxidative stress in hoof tissues, along with MSM and devil’s claw to promote a healthy inflammatory response and help manage discomfort in the foot. SmartLamina Pellets are specially designed to help maintain laminar health in easy keepers and horses with insulin resistance or pituitary dysfunction.
Nothing can ruin a day at the barn faster than bothersome bugs. Luckily for you and your horse, supplements in this category provide additional defense against these pesky pests. They help discourage flies from bothering and biting your horse, making riding and turnout time fun for both of you.