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Neigh-Lox® Advanced

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Feeding Chart

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Feeding Chart
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Inactive Dog - Less than 30 minutes of vigorous exercise daily
Active Dog - At least 30 minutes of vigorous exercise daily
Working Dog - More than two hours of vigorous exercise daily
This is only a guide. Please consult your veterinarian to determine the perfect feeding amount for your dog.
Only SmartPaks on AutoShip make you eligible to apply for the FREE ColiCare Program. Colicare is a free program that provides up to $15,000 in colic surgery reimbursement
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Please call 1-800-461-8898 to order this product.
Only SmartPaks on AutoShip make you eligible to apply for the FREE ColiCare Program. Colicare is a free program that provides up to $15,000 in colic surgery reimbursement
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Product Overview

Supports the GI tract from beginning to end

Support your horse’s digestive tract from beginning to end. Neigh-Lox Advanced® helps to maintain normal stomach function and digestive tract health. This formula includes: 

• Long-acting gastric buffering and coating agents support healthy gastric acid levels and normal stomach tissues

•  Saccharomyces boulardii  (a true probiotic) helps reduce the risk of hindgut imbalances and acidosis and may be helpful for horses with loose stool

•  Saccharomyces boulardii supplies nutrients that support the normal healing of damaged digestive tract tissues

• Proprietary yeast fermentation metabolites (prebiotics) support the growth and activity of beneficial bacteria throughout the GI tract 

The manufacturer recommends a SmartPak dosage of 1-2 scoops (2-4 oz) both AM and PM
  • Gastric buffer and coating agents support normal acid levels & maintain healthy stomach tissue
  • A combination of probiotics and prebiotics support a healthy microbiome and digestive tract tissues

Learn More

Key Ingredients


Supplement Facts

Ingredient Name Amount Per Serving
Ingredient Name Amount Per Pound

Ingredient Details


Weight Recommended Amount Loading Amount

How the Ingredients Work

Supporting Success

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The reviews provided on this website represent the experience of the individual posting the review. We do not adopt, edit, or endorse any of the submissions posted within the reviews section. Rather, the reviews are part of an online community of animal owners that desire to share their particular experience with other individuals. These reviews are not a substitute for discussing the health of your animal with a veterinarian.

SmartPak customers are some of the most conscientious animal owners around. We encourage you to share your experience with the products we sell to help fellow customers to make informed choices for their animals. We do not edit these reviews in any way - they are direct customer-to-customer communication. We do monitor reviews for positive and negative feedback, and use this feedback to improve our selection as well as sharing feedback with product manufacturers to help them improve their products. Please note that we recommend consulting your vet with serious health issues.

Neigh-Lox® Advanced is rated 4.6 out of 5 by 29.
Rated 4 out of 5 by from Works great! Bought this at the advice of a friend and vet and am so very happy with the results.
Date published: 2016-05-18
Rated 5 out of 5 by from Works great for tummy troubles My 10 year old Oldenburg gelding has a very sensitive stomach and this product works very well to keep his stomach issues under control.
Date published: 2016-01-17
Rated 4 out of 5 by from Great Product We bought a large warmblood who turned out to have rather severe ulcers. We have tried various vet recommended treatments and special diets but after 5 months he was still not healed. We added in the neigh-lox advanced in addition to his medications and it really seems to have helped a great deal. He's on his way to being totally healed and NO colic since we added it in.
Date published: 2015-10-05
Rated 5 out of 5 by from Great product? Our vet recommended this product for our show mare that came down with stomach issues. Started seeing results right away. I was skeptical but glad I ordered it.
Date published: 2015-06-16
Rated 5 out of 5 by from like I like this product. The difference was like day and night.
Date published: 2014-11-17
Rated 5 out of 5 by from Diarrhea gone!!! I decided to try this product after reading a review by someone with an old horse that had recurrent diarrhea. My horse, a 17 yr old WB, has been through it all: colic surgery too. His most persistent problem has been cow-pie diarrhea with a watery portion after passing manure. Also, worried about dehydration and colic too. He'd been treated with everything from sucralfate to Bio-Sponge, all to only very temporary results. I even had a specialist come out and Ultrasound his hind gut etc, all normal of course, $500 later. Any change in grass or environment (dry to wet, temperature changes, seasonal ) was enough to start the watery portion issue at least. No fun washing and or wrapping a tail in the winter, not to mention the extreme weightlifting of cleaning waterlogged piles out of his stall. This product has eliminated all of that, for months now. This is the only thing that seems to treat his hind gut issues. I also recommend Triple Crown Senior Feed and reducing hay amount to ease b urden on hind gut. Couldn't be happier!
Date published: 2014-10-05
Rated 5 out of 5 by from Works wonders on my 12 yr old gelding Bought this when my geldings ulcers were so bad he was basically emaciated. Now after being on it not even 6 months you can't see any ribs and he feels better.
Date published: 2014-07-26
Rated 4 out of 5 by from Not my favorite but... I think this is a good supplement for horses that have had ulcers, but I prefer SmartGut Ultra. This would be my second choice though because I have seen it help horses, but I have seen SmartGut Ultra help them more.
Date published: 2014-03-23
Rated 5 out of 5 by from Finally, no diarrhea OR Squirts! My 17 y.o. horse had colic surgery years back and has been very sensitive all along to any and all changes in the grass, weather etc. I could expect weeks of diarrhea and/or watery portions after passing manure any time he ate wet grass, had a change to richer hay, seasonal temp changes etc. This product along with SmartDigest Ultra are the only things that have gotten him to normal manure. Almost no "drippy butt" all winter long, even turned out after wet, snowy weather. We'll see how he does going into spring, he'll still wear a grazing muzzle, and I'll update my review then.
Date published: 2014-03-11
Rated 5 out of 5 by from LOVE THIS PRODUCT FOR OVERALL GUT HEALTH This product has kept my mare comfortable and colic free for over a year and a half. She was always very crabby when grooming especially over the left flank area and had an overall crabby attitude during collected work. She was colicing frequently but was always something that could be worked out without calling the vet every single time. I had her scoped and the results were unimpressive. I tried other products but they never seemed to work like this one. She is not crabby and no colic! This product is the best for all around gut health and palatable for the picky eater.
Date published: 2014-01-14
Rated 5 out of 5 by from Great Stuff! My picky, picky mare will eat this easily! And it helps tremendously with her ulcers. Many of the typical signs are diminished, including her nervous pacing.
Date published: 2013-12-30
Rated 5 out of 5 by from The best! This is the best supplement I have ever used. The ONLY supplement that I know acctually works because the difference was amazing! So happy the vet reccomended this, my mare is all better :)
Date published: 2013-12-11
Rated 5 out of 5 by from Great for keeping ulcers at bay! Tyler was on Neigh-Lox Advanced for two months (2 scoops 2x a day) and then we just switched him over to Neigh-Lox and he is doing great! He would be so unhappy with his saddle (which actually fits great) and whenever mounting he would grit his teeth and throw his head up. Now he doesn't throw a fuss for the saddle and is great for mounting. He gobbles up all his grain and is a much better hay eater now as well. Granted he has been on very nice grass all summer which has been great for his stomach too, but this stuff won't freeze (not a liquid) and it works great.
Date published: 2013-11-26
Rated 5 out of 5 by from Works great with a sensitive OTTB My TB mare was becoming more and more sensitive when brushing her girth, flank and wither area since she has been on Prevacox for arthritis. After researching products, I decided to try Neighlox Advanced. The results are positive, and my mare is no longer sensitive. I forgot to reorder after a trial, and my mare became cranky and sensitive. Now Neighlox Advanced is on auto ship so that wants happen again!
Date published: 2013-09-14
Rated 5 out of 5 by from Wonderful ulcer preventative I have used Neigh-Lox Advanced on a very sensitive OTTB who has been through ulcer treatment on two separate occasions. The first time, we treated based on the symptoms only(lost a lot of weight, coat condition was poor, lethargic, grumpy, bite marks on his left side). He was not put on an Ulcergard maintenance dose after treatment, but I tried several other alternatives (i.e. oat flour, pumpkin seeds, aloe vera juice, etc). The second time ulcers were suspected, we had him scoped. He was put on the maintenance dose of Ulcergard after going through the second treatment. I noticed that he was showing symptoms of ulcers again, even with the maintenance dose of UG. I decided to try Neigh-lox advanced after reading reviews and suspecting hind gut issues. This is the ONLY product that has worked. He was taken off of UG when we started the Neigh-lox advanced and has not been on a single dose of UG since. He has been to clinics, shows, etc and has not skipped a beat. His coat is shinier than ever, his personality is normal, and he has no bite marks on his side. I highly recommend this product as an alternative for ulcer prevention.
Date published: 2013-05-29
Rated 5 out of 5 by from great product I have an older geling with ulcer problems. Vet suggested this. I have noticed a big change in his attitude and he eats much better. I noticed a change after 3 days. He is a picky eater and loves this stuff. Very happy with the results.
Date published: 2013-04-29
Rated 5 out of 5 by from Working Great! We have been giving this to a standardbred trotting mare daily for over two months now. She eats much better, has gained a lot of weight and just looks awesome. All dappled out and instead of picking her grain she now dives right into it and finishes everything. Very happy! I combine it daily with Quitt and the combo seems to be exactly what she needed! Auto ship is so convenient and best $45 a month ever spent on a horse!
Date published: 2012-09-14
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